abstract：AIMS:Angiotensin-converting enzyme (ACE) inhibitors have been shown to reduce cardiovascular risk in different groups of patients. Whether these effects can be generalized to the broad group of patients with vascular disease is unknown. Therefore, we undertook a combined analysis using individual data from ADVANCE, EUR...

journal_title：European heart journal

authors： Brugts JJ,Ninomiya T,Boersma E,Remme WJ,Bertrand M,Ferrari R,Fox K,MacMahon S,Chalmers J,Simoons ML

更新日期：2009-06-01 00:00:00

abstract：AIMS:In patients with ischaemic left ventricular (LV) dysfunction and viable myocardium, revascularization improves systolic function. Diastolic dysfunction is also present in such patients; however, whether revascularization improves diastolic function also is largely unknown. METHODS:Twenty-six patients with chronic...

journal_title：European heart journal

authors： Carluccio E,Biagioli P,Alunni G,Murrone A,Leonelli V,Pantano P,Vincenti G,Giombolini C,Ragni T,Reboldi G,Gentile F,Ambrosio G

更新日期：2009-06-01 00:00:00

abstract：AIM:The purpose of this study was to assess the relationship between pulse pressure (PP) and cardiovascular outcomes in a large, elderly, coronary artery disease (CAD) population with hypertension, and compare the predictive power of PP with other blood pressure measures. METHODS AND RESULTS:In INternational VErapamil...

journal_title：European heart journal

authors： Bangalore S,Messerli FH,Franklin SS,Mancia G,Champion A,Pepine CJ

更新日期：2009-06-01 00:00:00

abstract：AIMS:Obesity is a recognized risk factor for atrial fibrillation (AF), partly because of the association between body mass index (BMI) and atrial volume. We aimed to determine whether other factors relating to body size were related to AF. METHODS AND RESULTS:Data were derived from a random population sample of 6903 m...

journal_title：European heart journal

authors： Rosengren A,Hauptman PJ,Lappas G,Olsson L,Wilhelmsen L,Swedberg K

更新日期：2009-05-01 00:00:00

abstract：AIMS:We sought to investigate the factors associated with restenosis and its potential association with late clinical deterioration after successful percutaneous mitral valvuloplasty (PMV). METHODS AND RESULTS:We analysed echocardiographic (median 74 months) and clinical (median 109 months) follow-up data of 329 patie...

journal_title：European heart journal

authors： Song JK,Song JM,Kang DH,Yun SC,Park DW,Lee SW,Kim YH,Lee CW,Hong MK,Kim JJ,Park SW,Park SJ

更新日期：2009-05-01 00:00:00

abstract：AIMS:This study assessed the relationship between inflammatory mediators and indices of infarct size and left-ventricular (LV) remodelling following successful primary percutaneous coronary intervention (PCI) in patients with first time ST elevation myocardial infarction (MI). METHODS AND RESULTS:Forty-two patients ad...

journal_title：European heart journal

authors： Ørn S,Manhenke C,Ueland T,Damås JK,Mollnes TE,Edvardsen T,Aukrust P,Dickstein K

更新日期：2009-05-01 00:00:00

abstract：AIMS:The aim of this study was to investigate the 12-month incidence, predictive factors, and prognosis of sustained ventricular tachycardia (VT) in chronic heart failure patients implanted with biventricular pacemakers without a back-up defibrillator (CRT-P), assessed by continuous intracardiac ventricular electrogram...

journal_title：European heart journal

authors： Boveda S,Marijon E,Jacob S,Defaye P,Winter JB,Bulava A,Gras D,Albenque JP,Combes N,Pavin D,Delarche N,Teubl A,Lambiez M,Chevalier P,Mona Lisa Study Group.

更新日期：2009-05-01 00:00:00

abstract：AIMS:To determine the effects of omega-3 polyunsaturated fatty acids (omega-3 PUFAs) from fish on the incidence of recurrent ventricular arrhythmia in implantable cardioverter defibrillator (ICD) patients by combining results from published trials. METHODS AND RESULTS:We searched in the Medline, EMBASE, and Cochrane d...

journal_title：European heart journal

authors： Brouwer IA,Raitt MH,Dullemeijer C,Kraemer DF,Zock PL,Morris C,Katan MB,Connor WE,Camm JA,Schouten EG,McAnulty J

更新日期：2009-04-01 00:00:00

abstract：AIMS:Cardiac dyssynchrony is common in patients with heart failure, whether or not they have ischaemic heart disease (IHD). The effect of the underlying cause of cardiac dysfunction on the response to cardiac resynchronization therapy (CRT) is unknown. This issue was addressed using data from the CARE-HF trial. METHOD...

journal_title：European heart journal

authors： Wikstrom G,Blomström-Lundqvist C,Andren B,Lönnerholm S,Blomström P,Freemantle N,Remp T,Cleland JG,CARE-HF study investigators.

更新日期：2009-04-01 00:00:00

abstract：AIMS:Prospective studies indicate that apolipoprotein measurements predict coronary heart disease (CHD) risk; however, evidence is conflicting, especially in the US. Our aim was to assess whether measurements of apolipoprotein B (apoB) and apolipoprotein A-I (apoA-I) can improve the ability to predict CHD death beyond ...

journal_title：European heart journal

authors： Sierra-Johnson J,Fisher RM,Romero-Corral A,Somers VK,Lopez-Jimenez F,Ohrvik J,Walldius G,Hellenius ML,Hamsten A

更新日期：2009-03-01 00:00:00

abstract：AIMS:Quantitative analysis of rest-stress myocardial perfusion magnetic resonance imaging (MRI) can provide assessments of regional myocardial perfusion reserve (MPR). The purpose of this study was to compare regional MPR determined by myocardial perfusion MRI with coronary flow reserve (CFR) by intracoronary Doppler f...

journal_title：European heart journal

authors： Kurita T,Sakuma H,Onishi K,Ishida M,Kitagawa K,Yamanaka T,Tanigawa T,Kitamura T,Takeda K,Ito M

更新日期：2009-02-01 00:00:00

abstract：AIMS:There is no cure for pulmonary arterial hypertension, but current approved treatment options include prostanoids, endothelin-receptor antagonists, and phosphodiesterase type-5 inhibitors. The effect on survival of these compounds has not been appropriately assessed in individual trials because of small sample size...

journal_title：European heart journal

authors： Galiè N,Manes A,Negro L,Palazzini M,Bacchi-Reggiani ML,Branzi A

更新日期：2009-02-01 00:00:00

abstract：AIMS:To assess EuroSCORE performance in predicting in-hospital mortality in on-pump coronary artery bypass grafting (CABG) and off-pump coronary artery bypass grafting (OPCAB). METHODS AND RESULTS:Additive and logistic EuroSCORE were computed for consecutive patients undergoing CABG (n = 3440, 75%) or OPCAB (n = 1140,...

journal_title：European heart journal

authors： Parolari A,Pesce LL,Trezzi M,Loardi C,Kassem S,Brambillasca C,Miguel B,Tremoli E,Biglioli P,Alamanni F

更新日期：2009-02-01 00:00:00

abstract：AIMS:The Occluded Artery Trial (OAT) (n = 2201) showed no benefit for routine percutaneous intervention (PCI) (n = 1101) over medical therapy (MED) (n = 1100) on the combined endpoint of death, myocardial infarction (MI), and class IV heart failure (congestive heart failure) in stable post-MI patients with late occlude...

journal_title：European heart journal

authors： Menon V,Pearte CA,Buller CE,Steg PG,Forman SA,White HD,Marino PN,Katritsis DG,Caramori P,Lasevitch R,Loboz-Grudzien K,Zurakowski A,Lamas GA,Hochman JS

更新日期：2009-01-01 00:00:00

abstract：AIMS:To assess the long-term benefit-risk ratio of drug-eluting (DES) vs. bare-metal stents (BMS) relative to stent size. METHODS AND RESULTS:All 826 consecutive BASKET (BAsel Stent Kosten-Effektivitäts Trial) patients randomized 2:1 to DES vs. BMS were followed after 3 years. Data were analysed separately for patient...

journal_title：European heart journal

authors： Pfisterer M,Brunner-La Rocca HP,Rickenbacher P,Hunziker P,Mueller C,Nietlispach F,Leibundgut G,Bader F,Kaiser C,BASKET.

更新日期：2009-01-01 00:00:00

abstract：AIMS:The curiosity that leanness is associated with poor survival in patients with chronic heart failure (CHF) needs further insight by investigating the impact of weight loss on prognosis in a large sample of patients across a broad spectrum of both reduced and preserved left ventricular (LV) systolic function. METHO...

journal_title：European heart journal

authors： Pocock SJ,McMurray JJ,Dobson J,Yusuf S,Granger CB,Michelson EL,Ostergren J,Pfeffer MA,Solomon SD,Anker SD,Swedberg KB

更新日期：2008-11-01 00:00:00

abstract：AIMS:Growth-differentiation factor-15 (GDF-15) has emerged as a biomarker of increased mortality and recurrent myocardial infarction (MI) in patients diagnosed with non-ST-elevation acute coronary syndrome. We explored the usefulness of GDF-15 for early risk stratification in 479 unselected patients with acute chest pa...

journal_title：European heart journal

authors： Eggers KM,Kempf T,Allhoff T,Lindahl B,Wallentin L,Wollert KC

更新日期：2008-10-01 00:00:00

abstract：:Non-thrombotic PE does not represent a distinct clinical syndrome. It may be due to a variety of embolic materials and result in a wide spectrum of clinical presentations, making the diagnosis difficult. With the exception of severe air and fat embolism, the haemodynamic consequences of non-thrombotic emboli are usual...

journal_title：European heart journal

authors： Torbicki A,Perrier A,Konstantinides S,Agnelli G,Galiè N,Pruszczyk P,Bengel F,Brady AJ,Ferreira D,Janssens U,Klepetko W,Mayer E,Remy-Jardin M,Bassand JP,ESC Committee for Practice Guidelines (CPG).

更新日期：2008-09-01 00:00:00

abstract：AIMS:This study evaluated the predictive value of NT-proBNP for patients with diabetes mellitus and compared the prognostic aptitude of this neurohumoral marker to traditional markers of cardiovascular events. METHODS AND RESULTS:A prospective observational study was conducted in 631 diabetic patients. The composite e...

journal_title：European heart journal

authors： Huelsmann M,Neuhold S,Strunk G,Moertl D,Berger R,Prager R,Abrahamian H,Riedl M,Pacher R,Luger A,Clodi M

更新日期：2008-09-01 00:00:00

abstract：AIMS:Effects of the bradycardic agent ivabradine on regional blood flow, contractile function, and infarct size were studied in a pig model of myocardial ischaemia/reperfusion. Heart rate reduction by beta-blockade is associated with negative inotropism and unmasked alpha-adrenergic coronary vasoconstriction. Ivabradin...

journal_title：European heart journal

authors： Heusch G,Skyschally A,Gres P,van Caster P,Schilawa D,Schulz R

更新日期：2008-09-01 00:00:00

abstract：AIMS:We evaluated the accuracy of 64-slice computed tomography (CT) to identify ischaemic aetiology of heart failure (IHF). METHODS AND RESULTS:Ninety-three consecutive patients in sinus rhythm with dilated cardiomyopathy but without suspicion of coronary artery disease (CAD) were enrolled when admitted for angiograph...

journal_title：European heart journal

authors： Ghostine S,Caussin C,Habis M,Habib Y,Clément C,Sigal-Cinqualbre A,Angel CY,Lancelin B,Capderou A,Paul JF

更新日期：2008-09-01 00:00:00

abstract：AIMS:To quantify the prevalence of coronary artery calcification (CAC) in relation to cardiovascular risk factors in marathon runners, and to study its role for myocardial damage and coronary events. METHODS AND RESULTS:In 108 apparently healthy male marathon runners aged >or=50 years, with >or=5 marathon competitions...

journal_title：European heart journal

authors： Möhlenkamp S,Lehmann N,Breuckmann F,Bröcker-Preuss M,Nassenstein K,Halle M,Budde T,Mann K,Barkhausen J,Heusch G,Jöckel KH,Erbel R,Marathon Study Investigators.,Heinz Nixdorf Recall Study Investigators.

更新日期：2008-08-01 00:00:00

abstract：AIMS:Cigarette smoking is a well-established risk factor for cardiovascular disease yet several studies have shown lower mortality after acute coronary syndromes in smokers compared with non-smokers, the so called 'smoker's paradox'. This study aimed to ascertain the relationship between smoking and clinical outcomes i...

journal_title：European heart journal

authors： Fonarow GC,Abraham WT,Albert NM,Stough WG,Gheorghiade M,Greenberg BH,O'Connor CM,Nunez E,Yancy CW,Young JB

更新日期：2008-08-01 00:00:00

abstract：AIMS:In animal models of obesity and diabetes mellitus, myocardial TG accumulation is associated with decreased myocardial function. In the physiologically ageing heart, myocardial triglyceride (TG) accumulation may also occur due to reduced myocardial fatty acid oxidation. The role of myocardial TG in the ageing human...

journal_title：European heart journal

authors： van der Meer RW,Rijzewijk LJ,Diamant M,Hammer S,Schär M,Bax JJ,Smit JW,Romijn JA,de Roos A,Lamb HJ

更新日期：2008-06-01 00:00:00

abstract：AIMS:We examined the adequacy of endogenous erythropoietin (EPO) levels for the degree of anaemia in patients with chronic heart failure (CHF) and its relation to prognosis. METHODS AND RESULTS:We studied 74 anaemic CHF patients from a cohort of 240 patients. The adequacy of endogenous EPO levels was assessed by deriv...

journal_title：European heart journal

authors： van der Meer P,Lok DJ,Januzzi JL,de la Porte PW,Lipsic E,van Wijngaarden J,Voors AA,van Gilst WH,van Veldhuisen DJ

更新日期：2008-06-01 00:00:00

abstract：AIMS:The aim of the study was to investigate the atrial myocardial deformation properties using ultrasound strain rate (SR) imaging in patients after catheter ablation of atrial fibrillation (AF) and to compare its prognostic value in maintaining sinus rhythm. METHODS AND RESULTS:A total of 118 patients with AF (74 pa...

journal_title：European heart journal

authors： Schneider C,Malisius R,Krause K,Lampe F,Bahlmann E,Boczor S,Antz M,Ernst S,Kuck KH

更新日期：2008-06-01 00:00:00

abstract：AIMS:To investigate whether Atorvastatin (Ator) treatment improves the cardiac micro-environment that facilitates survival and differentiation of bone-marrow-derived mesenchymal stem cells (MSCs) implanted in the post-infarct myocardium. METHODS AND RESULTS:Myocardial infarction was created by coronary ligation and im...

journal_title：European heart journal

authors： Yang YJ,Qian HY,Huang J,Geng YJ,Gao RL,Dou KF,Yang GS,Li JJ,Shen R,He ZX,Lu MJ,Zhao SH

更新日期：2008-06-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) is a member of the natriuretic peptide family that exerts various biological effects via acting on the receptor-guanylyl cyclase system, increasing the content of intracellular cyclic guanosine monophosphate (cGMP). ANP was first identified as a diuretic/natriuretic and vasodilating ho...

journal_title：European heart journal

authors： Kasama S,Furuya M,Toyama T,Ichikawa S,Kurabayashi M

更新日期：2008-06-01 00:00:00

abstract：AIMS:To compare two different clopidogrel regimens on the outcomes of patients undergoing elective coronary angiography (CAG)+/-ad hoc percutaneous coronary intervention (PCI). METHODS AND RESULTS:Open-trial randomized 1028 patients with stable angina to group A ('non-selective'-clopidogrel 600 mg > 6 h before CAG; n ...

journal_title：European heart journal

authors： Widimsky P,Motovská Z,Simek S,Kala P,Pudil R,Holm F,Petr R,Bílková D,Skalická H,Kuchynka P,Poloczek M,Miklík R,Maly M,Aschermann M,PRAGUE-8 Trial Investigators.

更新日期：2008-06-01 00:00:00

abstract：AIMS:To evaluate the predictive value of high sensitivity (hs) C-reactive protein levels on long-term survival in patients with ST-elevation myocardial infarction (STEMI) treated with primary PCI. METHODS AND RESULTS:We conducted a retrospective analysis of 758 STEMI patients (from January 2003 to December 2005), with...

journal_title：European heart journal

authors： Ortolani P,Marzocchi A,Marrozzini C,Palmerini T,Saia F,Taglieri N,Baldazzi F,Silenzi S,Bacchi-Reggiani ML,Guastaroba P,Grilli R,Branzi A

更新日期：2008-05-01 00:00:00

abstract：AIMS:To test the hypothesis that increasing age in patients presenting with high-risk non-ST-segment elevation acute coronary syndromes (NSTE-ACS) does not adversely influence the benefit of an early invasive strategy on major adverse events at 6 months. METHODS AND RESULTS:We report clinical outcomes in young (<70), ...

journal_title：European heart journal

authors： Devlin G,Gore JM,Elliott J,Wijesinghe N,Eagle KA,Avezum A,Huang W,Brieger D,GRACE Investigators.

更新日期：2008-05-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is the most frequent arrhythmia in humans. Rare familial forms exist. Recent evidence indicates a genetic susceptibility to common forms of AF. The alpha-subunit of the myocardial I(Kr)-channel, encoded by the KCNH2 gene, is crucial to ventricular and atrial repolarization. Patients with m...

journal_title：European heart journal

authors： Sinner MF,Pfeufer A,Akyol M,Beckmann BM,Hinterseer M,Wacker A,Perz S,Sauter W,Illig T,Näbauer M,Schmitt C,Wichmann HE,Schömig A,Steinbeck G,Meitinger T,Kääb S

更新日期：2008-04-01 00:00:00

abstract：AIMS:To investigate the association between neutrophil count, outcomes, and benefit of clopidogrel therapy in ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS:Baseline neutrophil count was measured in 2865 patients in CLARITY-TIMI 28, a randomized trial of clopidogrel vs. placebo in STEMI patients under...

journal_title：European heart journal

authors： O'Donoghue M,Morrow DA,Cannon CP,Guo W,Murphy SA,Gibson CM,Sabatine MS

更新日期：2008-04-01 00:00:00

abstract：:Chronic total occlusions (CTOs) are a subset of lesions that present a considerable burden to cardiovascular patients. There exists a strong clinical desire to improve non-surgical options for CTO revascularization. While several techniques, devices, and guide wires have been developed and refined for use in CTOs, the...

journal_title：European heart journal

authors： Courtney BK,Munce NR,Anderson KJ,Thind AS,Leung G,Radau PE,Foster FS,Vitkin IA,Schwartz RS,Dick AJ,Wright GA,Strauss BH

更新日期：2008-03-01 00:00:00

abstract：AIMS:Within the framework of the HYENA (hypertension and exposure to noise near airports) project we investigated the effect of short-term changes of transportation or indoor noise levels on blood pressure (BP) and heart rate (HR) during night-time sleep in 140 subjects living near four major European airports. METHOD...

journal_title：European heart journal

authors： Haralabidis AS,Dimakopoulou K,Vigna-Taglianti F,Giampaolo M,Borgini A,Dudley ML,Pershagen G,Bluhm G,Houthuijs D,Babisch W,Velonakis M,Katsouyanni K,Jarup L,HYENA Consortium.

更新日期：2008-03-01 00:00:00

abstract：AIMS:Brain natriuretic peptide (BNP), left ventricular (LV) systolic function, and mitral filling pattern (MFP) are prognostic indicators in patients with heart failure (HF). This study evaluated the potential role of E/Ea for predicting cardiovascular (CV) events in patients with suspected HF. This non-invasive measur...

journal_title：European heart journal

authors： Whalley GA,Wright SP,Pearl A,Gamble GD,Walsh HJ,Richards M,Doughty RN

更新日期：2008-02-01 00:00:00

abstract：AIMS:We examined the left lateral ridge (LLR) between the orifices of the left pulmonary veins and the left atrial appendage for a better understanding of its structural composition relevant to ablations for atrial fibrillation (AF). METHODS AND RESULTS:The LLR and its surrounding areas were studied in 40 heart specim...

journal_title：European heart journal

authors： Cabrera JA,Ho SY,Climent V,Sánchez-Quintana D

更新日期：2008-02-01 00:00:00

abstract：AIMS:This study investigates whether increased right ventricular (RV) pressure in pulmonary hypertension (PH) impairs right coronary artery (RCA) flow and RV perfusion. METHODS:In 25 subjects, five patients with idiopathic pulmonary arterial hypertension, nine patients with chronic thromboembolic pulmonary arterial hy...

journal_title：European heart journal

authors： van Wolferen SA,Marcus JT,Westerhof N,Spreeuwenberg MD,Marques KM,Bronzwaer JG,Henkens IR,Gan CT,Boonstra A,Postmus PE,Vonk-Noordegraaf A

更新日期：2008-01-01 00:00:00

abstract：AIMS:Previous analyses suggest only modest agreement between local site and core-laboratory (core-lab) electrocardiogram (ECG) interpretation in patients with acute coronary syndromes (ACSs); however, this has not been well examined outside of clinical trial populations. METHODS AND RESULTS:Patients (n = 5277 from 51 ...

journal_title：European heart journal

authors： Vijayaraghavan R,Yan AT,Tan M,Fitchett DH,Georgescu AA,Hassan Q,Langer A,Goodman SG,Canadian Acute Coronary Syndromes Registry Investigators.

更新日期：2008-01-01 00:00:00

abstract：AIMS:Circulating progenitor cells (PC) may contribute to myocardial recovery following infarction. Growth factors including VEGF are produced during ischaemia and stimulate PC release and activation. In this study, we focused on the functional chemotactic response of PC to VEGF in subjects early after myocardial ischae...

journal_title：European heart journal

authors： Vöö S,Eggermann J,Dunaeva M,Ramakers-van Oosterhoud C,Waltenberger J

更新日期：2008-01-01 00:00:00